Chemical synthesis of staphyloferrin A and its application for Staphylococcus aureus detection

Rajesh K. Pandey, Gregory G. Jarvis, Philip S. Low

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

The chemical synthesis of staphyloferrin A, a siderophore used by Staphylococcus bacteria for ferric iron retrieval, has been achieved with 79% yield via solid phase peptide synthesis (SPPS). Biological activity of synthetic staphyloferrin A has been confirmed by demonstrating its capture and uptake by live S. aureus.

Original languageEnglish (US)
Pages (from-to)1707-1710
Number of pages4
JournalOrganic and Biomolecular Chemistry
Volume12
Issue number11
DOIs
StatePublished - Mar 21 2014

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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