Chemical synthesis of staphyloferrin A and its application for Staphylococcus aureus detection

Rajesh K. Pandey; Gregory G. Jarvis; Philip S. Low

doi:10.1039/c3ob41230j

Chemical synthesis of staphyloferrin A and its application for Staphylococcus aureus detection

Rajesh K. Pandey, Gregory G. Jarvis, Philip S. Low

Houston Methodist

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

The chemical synthesis of staphyloferrin A, a siderophore used by Staphylococcus bacteria for ferric iron retrieval, has been achieved with 79% yield via solid phase peptide synthesis (SPPS). Biological activity of synthetic staphyloferrin A has been confirmed by demonstrating its capture and uptake by live S. aureus.

Original language	English (US)
Pages (from-to)	1707-1710
Number of pages	4
Journal	Organic and Biomolecular Chemistry
Volume	12
Issue number	11
DOIs	https://doi.org/10.1039/c3ob41230j
State	Published - Mar 21 2014

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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title = "Chemical synthesis of staphyloferrin A and its application for Staphylococcus aureus detection",

abstract = "The chemical synthesis of staphyloferrin A, a siderophore used by Staphylococcus bacteria for ferric iron retrieval, has been achieved with 79% yield via solid phase peptide synthesis (SPPS). Biological activity of synthetic staphyloferrin A has been confirmed by demonstrating its capture and uptake by live S. aureus.",

author = "Pandey, {Rajesh K.} and Jarvis, {Gregory G.} and Low, {Philip S.}",

year = "2014",

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language = "English (US)",

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AU - Pandey, Rajesh K.

AU - Jarvis, Gregory G.

AU - Low, Philip S.

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Y1 - 2014/3/21

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AB - The chemical synthesis of staphyloferrin A, a siderophore used by Staphylococcus bacteria for ferric iron retrieval, has been achieved with 79% yield via solid phase peptide synthesis (SPPS). Biological activity of synthetic staphyloferrin A has been confirmed by demonstrating its capture and uptake by live S. aureus.

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DO - 10.1039/c3ob41230j

M3 - Article

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AN - SCOPUS:84894466613

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JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

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ER -

Chemical synthesis of staphyloferrin A and its application for Staphylococcus aureus detection

Abstract

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