Abstract
The DNA of lymphomas from 12 AKXD recombinant inbred mouse strains was analyzed to determine the presence of somatically acquired ecotropic and mink cell focus-forming proviruses. Mink cell focus-forming proviruses were associated primarily with T-cel lymphomas, whereas ecotropic proviruses were associated with lymphomas of B-cell and myeloid lineages. A model based on the results is proposed to explain the variation in lymphoma types observed in different AKXD strains.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2929-2933 |
| Number of pages | 5 |
| Journal | Journal of virology |
| Volume | 61 |
| Issue number | 9 |
| DOIs | |
| State | Published - 1987 |
ASJC Scopus subject areas
- Microbiology
- Immunology
- Insect Science
- Virology
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