Characterization of DIP1, a novel nuclear protein in Drosophila melanogaster

Bruna De Felice, Robert Roy Wilson, Paolo Mondola, Gianfranco Matrone, Simona Damiano, Corrado Garbi, Luigi Nezi, Tin Tin Su

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

We have recently identified in Drosophila melanogaster a new gene encoding a nuclear protein, DIP1. Here we report the developmental expression and the finding that DIP1 subcellular localization is in the nucleus and at the nuclear periphery during interphase in embryos. Interestingly, in humans, DIP1 antibody identified signals in nuclei from cultured cells and reacted with a rough 30kDa protein in Western blotting experiments, demonstrating evolutionary conservation.

Original languageEnglish (US)
Pages (from-to)224-228
Number of pages5
JournalBiochemical and Biophysical Research Communications
Volume307
Issue number2
DOIs
StatePublished - Jul 25 2003

Keywords

  • Drosophila
  • Humans
  • Nuclear periphery protein
  • Nuclear protein

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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