TY - JOUR
T1 - Characterization of a wireless potentiostat for integration with a novel implantable biotransducer
AU - Kotanen, Christian N.
AU - Guiseppi-Elie, Anthony
N1 - Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 2014/3
Y1 - 2014/3
N2 - Wireless potentiostats are being developed and commercialized for use in the development of implantable electrochemical biosensors for the monitoring of physiological markers in a wide range of pathologies.The merits and drawbacks of the Pinnacle 8151 dual potentiostat were investigated for use with a novel implantable biotransducer, the dual responsive microdisc electrode array (MDEA 5037) of ABTECH Scientific.The potentiostat was evaluated with R and RC dummy cells and with MDEA transducers modified with polypyrrole-poly(2-hydroxyethyl methacrylate) electroconductive hydrogels that were all qualified by calibrated ac impedance spectroscopy.In a laboratory setting, the 8151 potentiostat maintained a steady and unbroken signal as far away as 75 ft(23 m),and when unobstructed,up to 100 ft (30 m).The error between the two channels was determined to be 6.4(0.3) and 0.70.1% for resistor-capacitor dummy cells RC=nominally 10MOmega;and 1 mu;F and resistor dummy cells (R=nominally} 10 M) respectively.The intra-channel variability was judged to be too large for exacting analyte determinations.
AB - Wireless potentiostats are being developed and commercialized for use in the development of implantable electrochemical biosensors for the monitoring of physiological markers in a wide range of pathologies.The merits and drawbacks of the Pinnacle 8151 dual potentiostat were investigated for use with a novel implantable biotransducer, the dual responsive microdisc electrode array (MDEA 5037) of ABTECH Scientific.The potentiostat was evaluated with R and RC dummy cells and with MDEA transducers modified with polypyrrole-poly(2-hydroxyethyl methacrylate) electroconductive hydrogels that were all qualified by calibrated ac impedance spectroscopy.In a laboratory setting, the 8151 potentiostat maintained a steady and unbroken signal as far away as 75 ft(23 m),and when unobstructed,up to 100 ft (30 m).The error between the two channels was determined to be 6.4(0.3) and 0.70.1% for resistor-capacitor dummy cells RC=nominally 10MOmega;and 1 mu;F and resistor dummy cells (R=nominally} 10 M) respectively.The intra-channel variability was judged to be too large for exacting analyte determinations.
KW - Biomedical telemetry
KW - biomedical transducers
KW - biosensors
KW - polypyrrole
KW - telemedicine
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U2 - 10.1109/JSEN.2013.2288059
DO - 10.1109/JSEN.2013.2288059
M3 - Article
AN - SCOPUS:84893081088
SN - 1530-437X
VL - 14
SP - 768
EP - 776
JO - IEEE Sensors Journal
JF - IEEE Sensors Journal
IS - 3
M1 - 6651733
ER -