Characterization of a wireless potentiostat for integration with a novel implantable biotransducer

Wireless potentiostats are being developed and commercialized for use in the development of implantable electrochemical biosensors for the monitoring of physiological markers in a wide range of pathologies.The merits and drawbacks of the Pinnacle 8151 dual potentiostat were investigated for use with a novel implantable biotransducer, the dual responsive microdisc electrode array (MDEA 5037) of ABTECH Scientific.The potentiostat was evaluated with R and RC dummy cells and with MDEA transducers modified with polypyrrole-poly(2-hydroxyethyl methacrylate) electroconductive hydrogels that were all qualified by calibrated ac impedance spectroscopy.In a laboratory setting, the 8151 potentiostat maintained a steady and unbroken signal as far away as 75 ft(23 m),and when unobstructed,up to 100 ft (30 m).The error between the two channels was determined to be 6.4(0.3) and 0.70.1% for resistor-capacitor dummy cells RC=nominally 10MOmega;and 1 mu;F and resistor dummy cells (R=nominally} 10 M) respectively.The intra-channel variability was judged to be too large for exacting analyte determinations.