Characterization of 3C-SiC (100) as a platform for detecting the onset of acute myocardial infarction (AMI)

Alexandra Oliveros; Anthony Guiseppi-Elie; Mark Jaroszeski; Stephen E. Saddow

doi:10.1557/opl.2012.1037

Characterization of 3C-SiC (100) as a platform for detecting the onset of acute myocardial infarction (AMI)

Alexandra Oliveros, Anthony Guiseppi-Elie, Mark Jaroszeski, Stephen E. Saddow

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Scopus citations

Abstract

In this work we describe the characterization of anti-myoglobin immobilization on 3C-SiC (100) by means of surface modification with 3-aminopropyltriethoxysilane (APTES). Surface water contact angle measurements were used to compare the wettability of 3C-SiC (100) before (16 ±3°) and after APTES layer formation (61 ±1°). Atomic force microscopy (AFM) was used to confirm the homogenous formation of APTES and anti-myoglobin immobilization with EDC-sulfo NHS coupling. For the APTES surfaces no significant change in the surface roughness was obtained whereas with anti-myoglobin surfaces, particles on the order of ∼60 nm in diameter with a globular shape were observed.

Original language	English (US)
Title of host publication	Silicon Carbide 2012 - Materials, Processing and Devices
Pages	37-40
Number of pages	4
DOIs	https://doi.org/10.1557/opl.2012.1037
State	Published - 2012
Event	2012 MRS Spring Meeting - San Francisco, CA, United States Duration: Apr 9 2012 → Apr 13 2012

Publication series

Name	Materials Research Society Symposium Proceedings
Volume	1433
ISSN (Print)	0272-9172

Other

Other	2012 MRS Spring Meeting
Country/Territory	United States
City	San Francisco, CA
Period	4/9/12 → 4/13/12

ASJC Scopus subject areas

Materials Science(all)
Condensed Matter Physics
Mechanics of Materials
Mechanical Engineering

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10.1557/opl.2012.1037

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Characterization of 3C-SiC (100) as a platform for detecting the onset of acute myocardial infarction (AMI). / Oliveros, Alexandra; Guiseppi-Elie, Anthony; Jaroszeski, Mark et al.

Silicon Carbide 2012 - Materials, Processing and Devices. 2012. p. 37-40 (Materials Research Society Symposium Proceedings; Vol. 1433).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Oliveros, A, Guiseppi-Elie, A, Jaroszeski, M & Saddow, SE 2012, Characterization of 3C-SiC (100) as a platform for detecting the onset of acute myocardial infarction (AMI). in Silicon Carbide 2012 - Materials, Processing and Devices. Materials Research Society Symposium Proceedings, vol. 1433, pp. 37-40, 2012 MRS Spring Meeting, San Francisco, CA, United States, 4/9/12. https://doi.org/10.1557/opl.2012.1037

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abstract = "In this work we describe the characterization of anti-myoglobin immobilization on 3C-SiC (100) by means of surface modification with 3-aminopropyltriethoxysilane (APTES). Surface water contact angle measurements were used to compare the wettability of 3C-SiC (100) before (16 ±3°) and after APTES layer formation (61 ±1°). Atomic force microscopy (AFM) was used to confirm the homogenous formation of APTES and anti-myoglobin immobilization with EDC-sulfo NHS coupling. For the APTES surfaces no significant change in the surface roughness was obtained whereas with anti-myoglobin surfaces, particles on the order of ∼60 nm in diameter with a globular shape were observed.",

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AU - Saddow, Stephen E.

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AB - In this work we describe the characterization of anti-myoglobin immobilization on 3C-SiC (100) by means of surface modification with 3-aminopropyltriethoxysilane (APTES). Surface water contact angle measurements were used to compare the wettability of 3C-SiC (100) before (16 ±3°) and after APTES layer formation (61 ±1°). Atomic force microscopy (AFM) was used to confirm the homogenous formation of APTES and anti-myoglobin immobilization with EDC-sulfo NHS coupling. For the APTES surfaces no significant change in the surface roughness was obtained whereas with anti-myoglobin surfaces, particles on the order of ∼60 nm in diameter with a globular shape were observed.

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Characterization of 3C-SiC (100) as a platform for detecting the onset of acute myocardial infarction (AMI)

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