TY - GEN
T1 - Characterization of 3C-SiC (100) as a platform for detecting the onset of acute myocardial infarction (AMI)
AU - Oliveros, Alexandra
AU - Guiseppi-Elie, Anthony
AU - Jaroszeski, Mark
AU - Saddow, Stephen E.
PY - 2012
Y1 - 2012
N2 - In this work we describe the characterization of anti-myoglobin immobilization on 3C-SiC (100) by means of surface modification with 3-aminopropyltriethoxysilane (APTES). Surface water contact angle measurements were used to compare the wettability of 3C-SiC (100) before (16 ±3°) and after APTES layer formation (61 ±1°). Atomic force microscopy (AFM) was used to confirm the homogenous formation of APTES and anti-myoglobin immobilization with EDC-sulfo NHS coupling. For the APTES surfaces no significant change in the surface roughness was obtained whereas with anti-myoglobin surfaces, particles on the order of ∼60 nm in diameter with a globular shape were observed.
AB - In this work we describe the characterization of anti-myoglobin immobilization on 3C-SiC (100) by means of surface modification with 3-aminopropyltriethoxysilane (APTES). Surface water contact angle measurements were used to compare the wettability of 3C-SiC (100) before (16 ±3°) and after APTES layer formation (61 ±1°). Atomic force microscopy (AFM) was used to confirm the homogenous formation of APTES and anti-myoglobin immobilization with EDC-sulfo NHS coupling. For the APTES surfaces no significant change in the surface roughness was obtained whereas with anti-myoglobin surfaces, particles on the order of ∼60 nm in diameter with a globular shape were observed.
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U2 - 10.1557/opl.2012.1037
DO - 10.1557/opl.2012.1037
M3 - Conference contribution
AN - SCOPUS:84879269307
SN - 9781627482400
T3 - Materials Research Society Symposium Proceedings
SP - 37
EP - 40
BT - Silicon Carbide 2012 - Materials, Processing and Devices
T2 - 2012 MRS Spring Meeting
Y2 - 9 April 2012 through 13 April 2012
ER -