Changes in transfusion therapy and reexploration rate after institution of a blood management program in cardiac surgical patients

Bruce D. Spiess, Bruce S.A. Gillies, Wayne Chandler, Edward Verrier

Research output: Contribution to journalArticle

240 Scopus citations

Abstract

A retrospective study was performed to determine the impact of a coagulation and transfusion management program on blood utilization in 1,079 sequential patients for myocardial revascularization and open ventricle or combined procedures. Four hundred and eighty-eight patients (group 1) before, and 591 patients (group 2) after institution of thromboelastography (TEG)-guided coagulation were studied and compared for transfusion requirements, donor exposure, and the incidence of reoperation for hemorrhage. Group 2 patients had a significantly lower incidence of overall transfusion (78.5% v 86.3%) during hospitalization and in total transfusion in the operating room (57.9% v 66.4%). The incidence of each transfusion subtype was also significantly lower in group 2 patients. Actual total median donor exposure was 8 in group 1 patients and 6 exposures in group 2 patients. Mediastinal reexploration for hemorrhage was 5.7% before institution of TEG-based coagulation monitoring and 1.5% in TEG-monitored patients. Use of TEG monitoring before reexploration has decreased the cost and potential risk for patients undergoing CABG surgery.

Original languageEnglish (US)
Pages (from-to)168-173
Number of pages6
JournalJournal of Cardiothoracic and Vascular Anesthesia
Volume9
Issue number2
DOIs
StatePublished - Apr 1995

Keywords

  • coagulation
  • hemorrhage
  • mediastinal reexploration
  • thromboelastography
  • transfusion

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Anesthesiology and Pain Medicine

Fingerprint Dive into the research topics of 'Changes in transfusion therapy and reexploration rate after institution of a blood management program in cardiac surgical patients'. Together they form a unique fingerprint.

Cite this