Cerebrospinal fluid creatine kinase activity and neurologic recovery after cardiac arrest

W. T. Longstreth; Kathleen J. Clayson; Wayne L. Chandler; S. Mark Sumi

doi:10.1212/wnl.34.6.834

Cerebrospinal fluid creatine kinase activity and neurologic recovery after cardiac arrest

W. T. Longstreth, Kathleen J. Clayson, Wayne L. Chandler, S. Mark Sumi

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

We evaluated prospectively the relation between cerebrospinal fluid creatine kinase activity (CSF CK) and neurologic recovery after out-of-hospital cardiac arrest. Without knowledge of the enzyme results, we determined whether patients awoke, followed commands, or had comprehensible speech. CSF CK was significantly higher in never-awakening than in awakening patients. After cardiac arrest, elevation of CSF CK predicts poor neurologic recovery.

Original language	English (US)
Pages (from-to)	834-837
Number of pages	4
Journal	Neurology
Volume	34
Issue number	6
DOIs	https://doi.org/10.1212/wnl.34.6.834
State	Published - Jun 1984
Externally published	Yes

ASJC Scopus subject areas

Clinical Neurology

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abstract = "We evaluated prospectively the relation between cerebrospinal fluid creatine kinase activity (CSF CK) and neurologic recovery after out-of-hospital cardiac arrest. Without knowledge of the enzyme results, we determined whether patients awoke, followed commands, or had comprehensible speech. CSF CK was significantly higher in never-awakening than in awakening patients. After cardiac arrest, elevation of CSF CK predicts poor neurologic recovery.",

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AB - We evaluated prospectively the relation between cerebrospinal fluid creatine kinase activity (CSF CK) and neurologic recovery after out-of-hospital cardiac arrest. Without knowledge of the enzyme results, we determined whether patients awoke, followed commands, or had comprehensible speech. CSF CK was significantly higher in never-awakening than in awakening patients. After cardiac arrest, elevation of CSF CK predicts poor neurologic recovery.

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Cerebrospinal fluid creatine kinase activity and neurologic recovery after cardiac arrest

Abstract

ASJC Scopus subject areas

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