Abstract
Subacute exposure of male rats to various concentrations (70-1000 ppm) of dichloromethane (DCM) produces a selective reduction of dopamine (DA) levels without a change of DA turnover in certain types of forebrain DA nerve terminal systems. In the low concentration (70 ppm) a selective reduction of DA turnover was observed in the medial palisade zone (MPZ) of the median eminence. This chlorinated organic solvent also produced a discrete dose-dependent increase of noradrenaline (NA) turnover within the.
Original language | English (US) |
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Pages (from-to) | 293-305 |
Number of pages | 13 |
Journal | Toxicology |
Volume | 29 |
Issue number | 4 |
DOIs | |
State | Published - Feb 1 1984 |
ASJC Scopus subject areas
- Toxicology