Central catecholamine neurons and exposure to dichloromethane. Selective changes in amine levels and turnover in tel- and diencephalic DA and NA nerve terminal systems and in the secretion of anterior pituitary hormones in the male rat

K. Fuxe; K. Andersson; T. Hansson; L. F. Agnati; P. Eneroth; J. Å Gustafsson

doi:10.1016/0300-483X(84)90161-6

Central catecholamine neurons and exposure to dichloromethane. Selective changes in amine levels and turnover in tel- and diencephalic DA and NA nerve terminal systems and in the secretion of anterior pituitary hormones in the male rat

K. Fuxe, K. Andersson, T. Hansson, L. F. Agnati, P. Eneroth, J. Å Gustafsson

Research output: Contribution to journal › Article

4 Scopus citations

Abstract

Subacute exposure of male rats to various concentrations (70-1000 ppm) of dichloromethane (DCM) produces a selective reduction of dopamine (DA) levels without a change of DA turnover in certain types of forebrain DA nerve terminal systems. In the low concentration (70 ppm) a selective reduction of DA turnover was observed in the medial palisade zone (MPZ) of the median eminence. This chlorinated organic solvent also produced a discrete dose-dependent increase of noradrenaline (NA) turnover within the.

Original language	English (US)
Pages (from-to)	293-305
Number of pages	13
Journal	Toxicology
Volume	29
Issue number	4
DOIs	https://doi.org/10.1016/0300-483X(84)90161-6
State	Published - Feb 1 1984

ASJC Scopus subject areas

Toxicology

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10.1016/0300-483X(84)90161-6

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Fuxe, K., Andersson, K., Hansson, T., Agnati, L. F., Eneroth, P., & Gustafsson, J. Å. (1984). Central catecholamine neurons and exposure to dichloromethane. Selective changes in amine levels and turnover in tel- and diencephalic DA and NA nerve terminal systems and in the secretion of anterior pituitary hormones in the male rat. Toxicology, 29(4), 293-305. https://doi.org/10.1016/0300-483X(84)90161-6

Central catecholamine neurons and exposure to dichloromethane. Selective changes in amine levels and turnover in tel- and diencephalic DA and NA nerve terminal systems and in the secretion of anterior pituitary hormones in the male rat. / Fuxe, K.; Andersson, K.; Hansson, T.; Agnati, L. F.; Eneroth, P.; Gustafsson, J. Å.

In: Toxicology, Vol. 29, No. 4, 01.02.1984, p. 293-305.

Research output: Contribution to journal › Article

Fuxe, K, Andersson, K, Hansson, T, Agnati, LF, Eneroth, P & Gustafsson, JÅ 1984, 'Central catecholamine neurons and exposure to dichloromethane. Selective changes in amine levels and turnover in tel- and diencephalic DA and NA nerve terminal systems and in the secretion of anterior pituitary hormones in the male rat', Toxicology, vol. 29, no. 4, pp. 293-305. https://doi.org/10.1016/0300-483X(84)90161-6

Fuxe K, Andersson K, Hansson T, Agnati LF, Eneroth P, Gustafsson JÅ. Central catecholamine neurons and exposure to dichloromethane. Selective changes in amine levels and turnover in tel- and diencephalic DA and NA nerve terminal systems and in the secretion of anterior pituitary hormones in the male rat. Toxicology. 1984 Feb 1;29(4):293-305. https://doi.org/10.1016/0300-483X(84)90161-6

Fuxe, K. ; Andersson, K. ; Hansson, T. ; Agnati, L. F. ; Eneroth, P. ; Gustafsson, J. Å. / Central catecholamine neurons and exposure to dichloromethane. Selective changes in amine levels and turnover in tel- and diencephalic DA and NA nerve terminal systems and in the secretion of anterior pituitary hormones in the male rat. In: Toxicology. 1984 ; Vol. 29, No. 4. pp. 293-305.

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