The CD28T-cell costimulatory molecule was shown to regulate in vivo migration of memory T cells independent of TCR stimulation, suggesting that CD28 can have additional functions beyond costimulation. However, the mechanism involved, the physiological relevance, and the therapeutic implications await further investigation.

Original languageEnglish (US)
Pages (from-to)2668-2669
Number of pages2
Issue number7
StatePublished - Apr 1 2007

ASJC Scopus subject areas

  • Biochemistry
  • Immunology
  • Hematology
  • Cell Biology

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