Case Report: Cardiac Tumor Resection And Repair With Porcine Xenograft

Walid K Abu Saleh, Odeaa Al Jabbari, Basel Ramlawi, Brian A Bruckner, Matthias Loebe, Michael J Reardon

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Primary cardiac sarcomas are rare and carry a grave prognosis. Improved survival requires a complete margin negative resection of the tumor. These surgical resections are often large and complex, requiring extensive reconstructive procedures. The appropriate material for cardiac reconstruction is not known. We have used glutaraldehyde-fixed bovine pericardium in our early series but have recently employed the MatriStem(®) Surgical Matrix PSMX membrane (ACell(®), Inc.; Columbia, MD), a unique proprietary urinary bladder matrix derived from porcine urinary bladder with the potential for viability and tissue ingrowth. In our study of six patients at this institution, all six underwent successful surgical resection and repair with the MatriStem acellular porcine urinary bladder membrane (ACell). The postoperative course was uncomplicated in all patients, and they are still alive at this time. An aggressive surgical approach to cardiac tumors can possibly lead to complete resection but often requires reconstruction of the cardiac tissue with a membrane. We were able to achieve acceptable results in our cardiac reconstruction by using the ACell extracellular matrix to reconstruct the defect following tumor resection. Longer-term follow-up in these patients, including imaging studies, will be necessary to demonstrate the durability and integrity of the reconstruction.

Original languageEnglish (US)
Pages (from-to)116-118
Number of pages3
JournalMethodist DeBakey cardiovascular journal
Issue number2
StatePublished - Apr 2016


  • ACell
  • Atrium
  • Cardiac reconstruction
  • Cardiac tumor
  • Right ventricle


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