Cardiovascular diseases - A major health risk in Asian Indians

Ranganathan Rajeshwari, Theresa A. Nicklas, Henry J. Pownall, Gerald S. Berenson

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

Cardiovascular disease (CVD) rates have been reported in several parts of the world and have been found to be unusually high in people originating from the Indian subcontinent. High coronary disease rates appear to be common to South Asian groups of different geographic origin, religion, and language. This presents a challenge for understanding the development of coronary heart disease. The high rates in Asian Indians are only partly explained with respect to elevated serum cholesterol, smoking, or hypertension. Low plasma high-density lipoprotein cholesterol, high plasma triacylglycerols, and high prevalence of type 2 diabetes mellitus have been consistently found in Asian Indians suggesting a state of insulin resistance. This review examines published data on the risk factors and prevalence of CVD in Indiana populations. Further studies are needed to determine if metabolic disturbances related to insulin can account for the high rates of CVD in Asian Indians and to identify possibilities for prevention.

Original languageEnglish (US)
Pages (from-to)515-533
Number of pages19
JournalNutrition Research
Volume25
Issue number6
DOIs
StatePublished - Jan 1 2005

Keywords

  • Asian Indians
  • Cardiovascular disease risk factors
  • Cardiovascular diseases

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

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