Cardiovascular Disease in Acromegaly

Morali D Sharma; Anh V Nguyen; Spandana Brown; Richard J Robbins

doi:10.14797/mdcj-13-2-64

Cardiovascular Disease in Acromegaly

Morali D Sharma, Anh V Nguyen, Spandana Brown, Richard J Robbins

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Abstract

In patients with acromegaly, chronic excess of growth hormone (GH) and insulin-like growth factor-1 (IGF-1) leads to the development of acromegalic cardiomyopathy. Its main features are biventricular hypertrophy, diastolic dysfunction, and in later stages, systolic dysfunction and congestive heart failure. Surgical and/or pharmacological treatment of acromegaly and control of cardiovascular risk factors help reverse some of these pathophysiologic changes and decrease the high risk of cardiovascular complications.

Original language	English (US)
Pages (from-to)	64-67
Number of pages	4
Journal	Methodist DeBakey cardiovascular journal
Volume	13
Issue number	2
DOIs	https://doi.org/10.14797/mdcj-13-2-64
State	Published - Jul 26 2017

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AU - Nguyen, Anh V

AU - Brown, Spandana

AU - Robbins, Richard J

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AB - In patients with acromegaly, chronic excess of growth hormone (GH) and insulin-like growth factor-1 (IGF-1) leads to the development of acromegalic cardiomyopathy. Its main features are biventricular hypertrophy, diastolic dysfunction, and in later stages, systolic dysfunction and congestive heart failure. Surgical and/or pharmacological treatment of acromegaly and control of cardiovascular risk factors help reverse some of these pathophysiologic changes and decrease the high risk of cardiovascular complications.

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Cardiovascular Disease in Acromegaly

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