TY - JOUR
T1 - Cardiac magnetic resonance findings in cardiac amyloidosis
AU - Dhore-Patil, Aneesh
AU - Modi, Vivek
AU - Gabr, El Moatasem
AU - Bersali, Akila
AU - Darwish, Amr
AU - Shah, Dipan
N1 - Publisher Copyright:
© 2024 Lippincott Williams and Wilkins. All rights reserved.
PY - 2024/9/1
Y1 - 2024/9/1
N2 - Purpose of reviewThe purpose of this review is to highlight the increasing importance of cardiac magnetic resonance (CMR) imaging in diagnosing and managing cardiac amyloidosis, especially given the recent advancements in treatment options.Recent findingsThis review emphasizes the crucial role of late gadolinium enhancement (LGE) with phase-sensitive inversion recovery (PSIR) techniques in both diagnosing and predicting patient outcomes in cardiac amyloidosis. The review also explores promising new techniques for diagnosing early-stage disease, such as native T1 mapping and ECV quantification. Additionally, it delves into experimental techniques like diffusion tensor imaging, MR elastography, and spectroscopy.SummaryThis review underscores CMR as a powerful tool for diagnosing cardiac amyloidosis, assessing risk factors, and monitoring treatment response. While LGE imaging remains the current best practice for diagnosis, emerging techniques such as T1 mapping and ECV quantification offer promise for improved detection, particularly in early stages of the disease. This has significant implications for patient management as newer therapeutic options become available for cardiac amyloidosis.
AB - Purpose of reviewThe purpose of this review is to highlight the increasing importance of cardiac magnetic resonance (CMR) imaging in diagnosing and managing cardiac amyloidosis, especially given the recent advancements in treatment options.Recent findingsThis review emphasizes the crucial role of late gadolinium enhancement (LGE) with phase-sensitive inversion recovery (PSIR) techniques in both diagnosing and predicting patient outcomes in cardiac amyloidosis. The review also explores promising new techniques for diagnosing early-stage disease, such as native T1 mapping and ECV quantification. Additionally, it delves into experimental techniques like diffusion tensor imaging, MR elastography, and spectroscopy.SummaryThis review underscores CMR as a powerful tool for diagnosing cardiac amyloidosis, assessing risk factors, and monitoring treatment response. While LGE imaging remains the current best practice for diagnosis, emerging techniques such as T1 mapping and ECV quantification offer promise for improved detection, particularly in early stages of the disease. This has significant implications for patient management as newer therapeutic options become available for cardiac amyloidosis.
KW - cardiac amyloidosis
KW - cardiac magnetic resonance
KW - extra cellular volume quantification
KW - gadolinium enhancement imaging
KW - light chain amyloidosis
KW - transthyretin amyloidosis
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U2 - 10.1097/HCO.0000000000001166
DO - 10.1097/HCO.0000000000001166
M3 - Review article
C2 - 38963426
AN - SCOPUS:85198666685
SN - 0268-4705
VL - 39
SP - 395
EP - 406
JO - Current Opinion in Cardiology
JF - Current Opinion in Cardiology
IS - 5
ER -