Cardiac activation mapping with ultrasound current source density imaging

Yexian Qin, Qian Li, Pier Ingram, Christy Barber, Zhonglin Liu, Russell S. Witte

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations


Ultrasound current source density imaging (UCSDI) is a noninvasive method for mapping electrical current based on the acoustoelectric (AE) effect. This technique can potentially overcome the limitations (i.e. poor resolution, inaccurate anatomical registration) of the conventional electrical mapping procedures typically used during treatment of sustained arrhythmias. In this study, UCSDI of the electrocardiogram (ECG) is demonstrated using a clinical electrophysiology catheter placed on the epicardium of the live rabbit heart. For the first time, 3-D cardiac activation maps are presented. Activation maps were used to calculate the cardiac conduction velocity for atrial pacing (1.31 m/s). We also demonstrated multi-electrode UCSDI for improving mapping accuracy by reducing the lied-field effect. This study indicates that UCSDI is potentially capable of real-time 3-D mapping of the cardiac activation wave, which would greatly facilitate ablation procedures for treatment of arrhythmias.

Original languageEnglish (US)
Title of host publicationIEEE International Ultrasonics Symposium, IUS
PublisherInstitute of Electrical and Electronics Engineers Inc.
Number of pages4
ISBN (Electronic)9781479970490
StatePublished - Oct 20 2014
Event2014 IEEE International Ultrasonics Symposium, IUS 2014 - Chicago, United States
Duration: Sep 3 2014Sep 6 2014

Publication series

NameIEEE International Ultrasonics Symposium, IUS
ISSN (Print)1948-5719
ISSN (Electronic)1948-5727


Conference2014 IEEE International Ultrasonics Symposium, IUS 2014
Country/TerritoryUnited States


  • acousto-electric
  • cardiac activation
  • cardiac arrhythmia
  • cardiac mapping
  • electrocardiogram (ECG/EKG)

ASJC Scopus subject areas

  • Acoustics and Ultrasonics


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