Carcinoembryonic antigen in basal cell neoplasms in black patients: An immunohistochemical study

Melanie K. Kidd; Jaime A. Tschen; Ted Rosen; Andrew R. Altman; Leonard Harry Goldberg

doi:10.1016/S0190-9622(89)70290-5

Carcinoembryonic antigen in basal cell neoplasms in black patients: An immunohistochemical study

Melanie K. Kidd, Jaime A. Tschen, Ted Rosen, Andrew R. Altman, Leonard Harry Goldberg

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

The development of skin cancer in black persons is rare, and basal cell epitheliomas are the most uncommon. Eight tumors were evaluated by routine histochemistry examination and immunoperoxidase staining for carcinoembryonic antigen (CEA). Our results demonstrate that half these tumors showed a positive reaction to this antigen, supporting the adnexal origin/differentiation of these lesions. Sixteen (16/18) similar tumors from white patients failed to show equivalent features. In addition, some of these CEA-positive tumors seem to demonstrate less aggressive behavior.

Original language	English (US)
Pages (from-to)	1007-1010
Number of pages	4
Journal	Journal of the American Academy of Dermatology
Volume	21
Issue number	5
DOIs	https://doi.org/10.1016/S0190-9622(89)70290-5
State	Published - Jan 1 1989

ASJC Scopus subject areas

Dermatology

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title = "Carcinoembryonic antigen in basal cell neoplasms in black patients: An immunohistochemical study",

abstract = "The development of skin cancer in black persons is rare, and basal cell epitheliomas are the most uncommon. Eight tumors were evaluated by routine histochemistry examination and immunoperoxidase staining for carcinoembryonic antigen (CEA). Our results demonstrate that half these tumors showed a positive reaction to this antigen, supporting the adnexal origin/differentiation of these lesions. Sixteen (16/18) similar tumors from white patients failed to show equivalent features. In addition, some of these CEA-positive tumors seem to demonstrate less aggressive behavior.",

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T1 - Carcinoembryonic antigen in basal cell neoplasms in black patients

T2 - An immunohistochemical study

AU - Kidd, Melanie K.

AU - Tschen, Jaime A.

AU - Rosen, Ted

AU - Altman, Andrew R.

AU - Goldberg, Leonard Harry

PY - 1989/1/1

Y1 - 1989/1/1

N2 - The development of skin cancer in black persons is rare, and basal cell epitheliomas are the most uncommon. Eight tumors were evaluated by routine histochemistry examination and immunoperoxidase staining for carcinoembryonic antigen (CEA). Our results demonstrate that half these tumors showed a positive reaction to this antigen, supporting the adnexal origin/differentiation of these lesions. Sixteen (16/18) similar tumors from white patients failed to show equivalent features. In addition, some of these CEA-positive tumors seem to demonstrate less aggressive behavior.

AB - The development of skin cancer in black persons is rare, and basal cell epitheliomas are the most uncommon. Eight tumors were evaluated by routine histochemistry examination and immunoperoxidase staining for carcinoembryonic antigen (CEA). Our results demonstrate that half these tumors showed a positive reaction to this antigen, supporting the adnexal origin/differentiation of these lesions. Sixteen (16/18) similar tumors from white patients failed to show equivalent features. In addition, some of these CEA-positive tumors seem to demonstrate less aggressive behavior.

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JO - Journal of the American Academy of Dermatology

JF - Journal of the American Academy of Dermatology

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Carcinoembryonic antigen in basal cell neoplasms in black patients: An immunohistochemical study

Abstract

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