TY - JOUR
T1 - Carcinoembryonic antigen in basal cell neoplasms in black patients
T2 - An immunohistochemical study
AU - Kidd, Melanie K.
AU - Tschen, Jaime A.
AU - Rosen, Ted
AU - Altman, Andrew R.
AU - Goldberg, Leonard Harry
PY - 1989/1/1
Y1 - 1989/1/1
N2 - The development of skin cancer in black persons is rare, and basal cell epitheliomas are the most uncommon. Eight tumors were evaluated by routine histochemistry examination and immunoperoxidase staining for carcinoembryonic antigen (CEA). Our results demonstrate that half these tumors showed a positive reaction to this antigen, supporting the adnexal origin/differentiation of these lesions. Sixteen (16/18) similar tumors from white patients failed to show equivalent features. In addition, some of these CEA-positive tumors seem to demonstrate less aggressive behavior.
AB - The development of skin cancer in black persons is rare, and basal cell epitheliomas are the most uncommon. Eight tumors were evaluated by routine histochemistry examination and immunoperoxidase staining for carcinoembryonic antigen (CEA). Our results demonstrate that half these tumors showed a positive reaction to this antigen, supporting the adnexal origin/differentiation of these lesions. Sixteen (16/18) similar tumors from white patients failed to show equivalent features. In addition, some of these CEA-positive tumors seem to demonstrate less aggressive behavior.
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U2 - 10.1016/S0190-9622(89)70290-5
DO - 10.1016/S0190-9622(89)70290-5
M3 - Article
C2 - 2808813
AN - SCOPUS:0024417315
SN - 0190-9622
VL - 21
SP - 1007
EP - 1010
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
IS - 5
ER -