Carcinoembryonic antigen in basal cell neoplasms in black patients: An immunohistochemical study

Melanie K. Kidd, Jaime A. Tschen, Ted Rosen, Andrew R. Altman, Leonard Harry Goldberg

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

The development of skin cancer in black persons is rare, and basal cell epitheliomas are the most uncommon. Eight tumors were evaluated by routine histochemistry examination and immunoperoxidase staining for carcinoembryonic antigen (CEA). Our results demonstrate that half these tumors showed a positive reaction to this antigen, supporting the adnexal origin/differentiation of these lesions. Sixteen (16/18) similar tumors from white patients failed to show equivalent features. In addition, some of these CEA-positive tumors seem to demonstrate less aggressive behavior.

Original languageEnglish (US)
Pages (from-to)1007-1010
Number of pages4
JournalJournal of the American Academy of Dermatology
Volume21
Issue number5
DOIs
StatePublished - Jan 1 1989

ASJC Scopus subject areas

  • Dermatology

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