Carbon nanotubes assisted biomimetic synthesis of hydroxyapatite from simulated body fluid

Santosh Aryal; Shanta Raj Bhattarai; Remant Bahadur Remant; Myung Seob Khil; Duck Rae Lee; Hak Yong Kim

doi:10.1016/j.msea.2006.04.004

Carbon nanotubes assisted biomimetic synthesis of hydroxyapatite from simulated body fluid

Santosh Aryal, Shanta Raj Bhattarai, Remant Bahadur Remant, Myung Seob Khil, Duck Rae Lee, Hak Yong Kim

Houston Methodist

Research output: Contribution to journal › Article › peer-review

88 Scopus citations

Abstract

Synthesis of hydroxyapatite (HA) using carboxylated carbon nanotubes were investigated using simulated body fluid (SBF) similar to physiological condition and products tailored to have chemistry found to mimic natural bone. Composites were synthesized under ambient condition and physiological temperature (37 °C). Former results the formation of dense net over carbon nanotubes even after 21 days of reaction, a hierarchy assemblies, whereas later results the formation of large crystals after 7 days of reaction. Physico-chemical characterization of composite material showed that the nucleation of HA initiates through the carboxyl group. Different parameters like temperature and reaction time were found to control the crystallization of HA. After 7 days of reaction, the crystal becames denser and directs towards the single plane; (0 0 2), thereby showing its phase purity. The result showed that the carboxylated carbon nanotubes were capable to nucleate HA from SBF, which can be used as a biomaterial for the modification of implant materials.

Original language	English (US)
Pages (from-to)	202-207
Number of pages	6
Journal	Materials Science and Engineering A
Volume	426
Issue number	1-2
DOIs	https://doi.org/10.1016/j.msea.2006.04.004
State	Published - Jun 25 2006

Keywords

Biomaterials
Biomimetic
Biomineralization
Carbon nanotubes
Hydroxyapatite

ASJC Scopus subject areas

General Materials Science

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10.1016/j.msea.2006.04.004

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title = "Carbon nanotubes assisted biomimetic synthesis of hydroxyapatite from simulated body fluid",

abstract = "Synthesis of hydroxyapatite (HA) using carboxylated carbon nanotubes were investigated using simulated body fluid (SBF) similar to physiological condition and products tailored to have chemistry found to mimic natural bone. Composites were synthesized under ambient condition and physiological temperature (37 °C). Former results the formation of dense net over carbon nanotubes even after 21 days of reaction, a hierarchy assemblies, whereas later results the formation of large crystals after 7 days of reaction. Physico-chemical characterization of composite material showed that the nucleation of HA initiates through the carboxyl group. Different parameters like temperature and reaction time were found to control the crystallization of HA. After 7 days of reaction, the crystal becames denser and directs towards the single plane; (0 0 2), thereby showing its phase purity. The result showed that the carboxylated carbon nanotubes were capable to nucleate HA from SBF, which can be used as a biomaterial for the modification of implant materials.",

keywords = "Biomaterials, Biomimetic, Biomineralization, Carbon nanotubes, Hydroxyapatite",

author = "Santosh Aryal and Bhattarai, {Shanta Raj} and Remant, {Remant Bahadur} and Khil, {Myung Seob} and Lee, {Duck Rae} and Kim, {Hak Yong}",

note = "Funding Information: This research was supported by the Korean Ministry of Education and Human Resource Development through the Center for Healthcare Technology Development, Chonbuk National University, Jeonju 561-756, Republic of Korea. We thank Dr. N. Dharmaraj, Department of Chemistry, Government Arts College, Udumalpet 642 126, India for helpful discussions.",

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doi = "10.1016/j.msea.2006.04.004",

language = "English (US)",

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AU - Aryal, Santosh

AU - Bhattarai, Shanta Raj

AU - Remant, Remant Bahadur

AU - Khil, Myung Seob

AU - Lee, Duck Rae

AU - Kim, Hak Yong

N1 - Funding Information: This research was supported by the Korean Ministry of Education and Human Resource Development through the Center for Healthcare Technology Development, Chonbuk National University, Jeonju 561-756, Republic of Korea. We thank Dr. N. Dharmaraj, Department of Chemistry, Government Arts College, Udumalpet 642 126, India for helpful discussions.

PY - 2006/6/25

Y1 - 2006/6/25

N2 - Synthesis of hydroxyapatite (HA) using carboxylated carbon nanotubes were investigated using simulated body fluid (SBF) similar to physiological condition and products tailored to have chemistry found to mimic natural bone. Composites were synthesized under ambient condition and physiological temperature (37 °C). Former results the formation of dense net over carbon nanotubes even after 21 days of reaction, a hierarchy assemblies, whereas later results the formation of large crystals after 7 days of reaction. Physico-chemical characterization of composite material showed that the nucleation of HA initiates through the carboxyl group. Different parameters like temperature and reaction time were found to control the crystallization of HA. After 7 days of reaction, the crystal becames denser and directs towards the single plane; (0 0 2), thereby showing its phase purity. The result showed that the carboxylated carbon nanotubes were capable to nucleate HA from SBF, which can be used as a biomaterial for the modification of implant materials.

AB - Synthesis of hydroxyapatite (HA) using carboxylated carbon nanotubes were investigated using simulated body fluid (SBF) similar to physiological condition and products tailored to have chemistry found to mimic natural bone. Composites were synthesized under ambient condition and physiological temperature (37 °C). Former results the formation of dense net over carbon nanotubes even after 21 days of reaction, a hierarchy assemblies, whereas later results the formation of large crystals after 7 days of reaction. Physico-chemical characterization of composite material showed that the nucleation of HA initiates through the carboxyl group. Different parameters like temperature and reaction time were found to control the crystallization of HA. After 7 days of reaction, the crystal becames denser and directs towards the single plane; (0 0 2), thereby showing its phase purity. The result showed that the carboxylated carbon nanotubes were capable to nucleate HA from SBF, which can be used as a biomaterial for the modification of implant materials.

KW - Biomaterials

KW - Biomimetic

KW - Biomineralization

KW - Carbon nanotubes

KW - Hydroxyapatite

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Carbon nanotubes assisted biomimetic synthesis of hydroxyapatite from simulated body fluid

Abstract

Keywords

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