Collagen matrices have been neoglycosylated with lactose by reductive amination at lysine side chains. AFM analysis highlights that the chemical does not affect molecular assembly into fibrils. Moreover, ELLA biochemical assays show that the glycan moiety is efficiently exposed on the matrix surface for receptor recognition.
- Biocompatible Materials
- Carbohydrate Conformation
- Drug Design
- Molecular Dynamics Simulation
- Journal Article
- Research Support, Non-U.S. Gov't