Cancer stem cells

Kyuson Yun, Barbara Tennent

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


The recent identification of a subpopulation of cancer cells with characteristics of somatic stem cells and tumor-initiating capacity [1-5] is causing a paradigm shift in the way we think about anti-cancer therapies. Growing evidence suggests cancer stem cells uniquely propagate many malignancies and are resistant to conventional therapies. Targeting these cells is essential for chronic and curative therapy. Here, we review the use of in vitro and in vivo models for cancer stem cell research.

Original languageEnglish (US)
Pages (from-to)47-52
Number of pages6
JournalDrug Discovery Today: Disease Models
Issue number2
StatePublished - 2007

ASJC Scopus subject areas

  • Molecular Medicine
  • Drug Discovery


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