Cancer stem cells

Kyuson Yun, Barbara Tennent

    Research output: Contribution to journalReview articlepeer-review

    2 Scopus citations

    Abstract

    The recent identification of a subpopulation of cancer cells with characteristics of somatic stem cells and tumor-initiating capacity [1-5] is causing a paradigm shift in the way we think about anti-cancer therapies. Growing evidence suggests cancer stem cells uniquely propagate many malignancies and are resistant to conventional therapies. Targeting these cells is essential for chronic and curative therapy. Here, we review the use of in vitro and in vivo models for cancer stem cell research.

    Original languageEnglish (US)
    Pages (from-to)47-52
    Number of pages6
    JournalDrug Discovery Today: Disease Models
    Volume4
    Issue number2
    DOIs
    StatePublished - 2007

    ASJC Scopus subject areas

    • Molecular Medicine
    • Drug Discovery

    Fingerprint

    Dive into the research topics of 'Cancer stem cells'. Together they form a unique fingerprint.

    Cite this