Burkholderia gladioli osteomyelitis in association with chronic granulomatous disease: Case report and review

Bobby L. Boyanton; Lenora M. Noroski; Hari Reddy; Megan K. Dishop; M. John Hicks; James Versalovic; Edina H. Moylett

doi:10.1097/01.inf.0000177285.44374.dc

Burkholderia gladioli osteomyelitis in association with chronic granulomatous disease: Case report and review

Bobby L. Boyanton, Lenora M. Noroski, Hari Reddy, Megan K. Dishop, M. John Hicks, James Versalovic, Edina H. Moylett

Houston Methodist

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

We describe a case of insidious small bone osteomyelitis and soft tissue abscess with Burkholderia gladioli in a 6-year-old Caucasian boy with chronic granulomatous disease. DNA sequencing of the 16S ribosomal RNA gene confirmed the bacterial identification. Clinical cure was achieved with a combination of antimicrobial therapy and surgical debridement. A review of infections caused by Burkholderia spp., other than Burkholderia cepacia complex, in pediatric patients with chronic granulomatous disease is provided.

Original language	English (US)
Pages (from-to)	837-839
Number of pages	3
Journal	Pediatric Infectious Disease Journal
Volume	24
Issue number	9
DOIs	https://doi.org/10.1097/01.inf.0000177285.44374.dc
State	Published - Jan 1 2005

Keywords

Burkholderia gladioli
Chronic granulomatous disease
DNA sequencing
Molecular diagnostics
Osteomyelitis
Pyrosequencing

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Microbiology (medical)

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10.1097/01.inf.0000177285.44374.dc

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title = "Burkholderia gladioli osteomyelitis in association with chronic granulomatous disease: Case report and review",

abstract = "We describe a case of insidious small bone osteomyelitis and soft tissue abscess with Burkholderia gladioli in a 6-year-old Caucasian boy with chronic granulomatous disease. DNA sequencing of the 16S ribosomal RNA gene confirmed the bacterial identification. Clinical cure was achieved with a combination of antimicrobial therapy and surgical debridement. A review of infections caused by Burkholderia spp., other than Burkholderia cepacia complex, in pediatric patients with chronic granulomatous disease is provided.",

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AU - Hicks, M. John

AU - Versalovic, James

AU - Moylett, Edina H.

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AB - We describe a case of insidious small bone osteomyelitis and soft tissue abscess with Burkholderia gladioli in a 6-year-old Caucasian boy with chronic granulomatous disease. DNA sequencing of the 16S ribosomal RNA gene confirmed the bacterial identification. Clinical cure was achieved with a combination of antimicrobial therapy and surgical debridement. A review of infections caused by Burkholderia spp., other than Burkholderia cepacia complex, in pediatric patients with chronic granulomatous disease is provided.

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KW - DNA sequencing

KW - Molecular diagnostics

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KW - Pyrosequencing

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Burkholderia gladioli osteomyelitis in association with chronic granulomatous disease: Case report and review

Abstract

Keywords

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