Brain metastasis initial presentation of breast cancer: DNA flow cytometric comparison of two sites

Jungsil Ro; Jae Y. Ro; Adel El-Naggar; Frankie A. Holmes; David Close; Gabriel N. Hortobagyi

Brain metastasis initial presentation of breast cancer: DNA flow cytometric comparison of two sites

Jungsil Ro, Jae Y. Ro, Adel El-Naggar, Frankie A. Holmes, David Close, Gabriel N. Hortobagyi

Research output: Contribution to journal › Article › peer-review

Abstract

The case of a metastatic brain tumor that antedated the diagnosis of a small primary breast cancer (T₁, N_o) by 2 months in a 38-year-old woman is reported. DNA flow cytometry showed similar clonal populations for the primary and metastatic tumors, but the metastatic site had a larger aneuploid population and a higher S-phase fraction. This unusual presentation may be explained by the faster tumor growth rate of the metastatic site as determined by DNA flow cytometry.

Original language	English (US)
Pages (from-to)	35-38
Number of pages	4
Journal	Breast Disease
Volume	3
Issue number	1
State	Published - May 1990

Keywords

breast cancer
DNA flow cytometry
metastatic brain tumor

ASJC Scopus subject areas

Surgery

Cite this

@article{168fd9c743f34bca8e99880203047160,

title = "Brain metastasis initial presentation of breast cancer: DNA flow cytometric comparison of two sites",

abstract = "The case of a metastatic brain tumor that antedated the diagnosis of a small primary breast cancer (T1, No) by 2 months in a 38-year-old woman is reported. DNA flow cytometry showed similar clonal populations for the primary and metastatic tumors, but the metastatic site had a larger aneuploid population and a higher S-phase fraction. This unusual presentation may be explained by the faster tumor growth rate of the metastatic site as determined by DNA flow cytometry.",

keywords = "breast cancer, DNA flow cytometry, metastatic brain tumor",

author = "Jungsil Ro and Ro, \{Jae Y.\} and Adel El-Naggar and Holmes, \{Frankie A.\} and David Close and Hortobagyi, \{Gabriel N.\}",

year = "1990",

month = may,

language = "English (US)",

volume = "3",

pages = "35--38",

journal = "Breast Disease",

issn = "0888-6008",

publisher = "SAGE Publications Ltd",

number = "1",

}

TY - JOUR

T1 - Brain metastasis initial presentation of breast cancer

T2 - DNA flow cytometric comparison of two sites

AU - Ro, Jungsil

AU - Ro, Jae Y.

AU - El-Naggar, Adel

AU - Holmes, Frankie A.

AU - Close, David

AU - Hortobagyi, Gabriel N.

PY - 1990/5

Y1 - 1990/5

N2 - The case of a metastatic brain tumor that antedated the diagnosis of a small primary breast cancer (T1, No) by 2 months in a 38-year-old woman is reported. DNA flow cytometry showed similar clonal populations for the primary and metastatic tumors, but the metastatic site had a larger aneuploid population and a higher S-phase fraction. This unusual presentation may be explained by the faster tumor growth rate of the metastatic site as determined by DNA flow cytometry.

AB - The case of a metastatic brain tumor that antedated the diagnosis of a small primary breast cancer (T1, No) by 2 months in a 38-year-old woman is reported. DNA flow cytometry showed similar clonal populations for the primary and metastatic tumors, but the metastatic site had a larger aneuploid population and a higher S-phase fraction. This unusual presentation may be explained by the faster tumor growth rate of the metastatic site as determined by DNA flow cytometry.

KW - breast cancer

KW - DNA flow cytometry

KW - metastatic brain tumor

UR - https://www.scopus.com/pages/publications/45149136960

UR - https://www.scopus.com/inward/citedby.url?scp=45149136960&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:45149136960

SN - 0888-6008

VL - 3

SP - 35

EP - 38

JO - Breast Disease

JF - Breast Disease

IS - 1

ER -

Brain metastasis initial presentation of breast cancer: DNA flow cytometric comparison of two sites

Abstract

Keywords

ASJC Scopus subject areas

Other files and links

Fingerprint

Cite this