Brain metastasis initial presentation of breast cancer: DNA flow cytometric comparison of two sites

Jungsil Ro, Jae Y. Ro, Adel El-Naggar, Frankie A. Holmes, David Close, Gabriel N. Hortobagyi

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

The case of a metastatic brain tumor that antedated the diagnosis of a small primary breast cancer (T1, No) by 2 months in a 38-year-old woman is reported. DNA flow cytometry showed similar clonal populations for the primary and metastatic tumors, but the metastatic site had a larger aneuploid population and a higher S-phase fraction. This unusual presentation may be explained by the faster tumor growth rate of the metastatic site as determined by DNA flow cytometry.

Original languageEnglish (US)
Pages (from-to)35-38
Number of pages4
JournalBreast Disease
Volume3
Issue number1
StatePublished - May 1990

Keywords

  • breast cancer
  • DNA flow cytometry
  • metastatic brain tumor

ASJC Scopus subject areas

  • Surgery

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