Bleeding esophageal varices and portal vein thrombosis after pancreatic mixed-cell autotransplantation

L. Memsic, R. W. Busuttil, L. W. Traverso

Research output: Contribution to journalArticlepeer-review

43 Scopus citations

Abstract

A patient with chronic pancreatitis caused by congenital pancreatic duct atresia underwent total pancreatectomy and mixed-cell pancreatic autotransplantation by portal vein embolization. Two years later she developed massive upper gastrointestinal bleeding from gastroesophageal varices and required a mesocaval H graft. The cause of the portal hypertension was portal vein thrombosis caused by portal vein infusion of pancreatic homogenate, and it represents a serious complication of the procedure. Although this is the second report of portal hypertension that required portasystemic shunting after islet cell autotransplantation, it is the first reported case of the development of bleeding esophageal varices caused by portal vein thrombosis after pancreatic islet cell transplantation.

Original languageEnglish (US)
Pages (from-to)238-242
Number of pages5
JournalSurgery
Volume95
Issue number2
StatePublished - 1984

ASJC Scopus subject areas

  • Surgery

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