Biosynthesis op 16α-hydroxyprogesterone by human fetal liver microsomes

B. P. Lisboa, J. Å Gustafsson

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

16α-Hydroxyprogesterone has been isolated and characterized after incubation of 4-[14C]-progesterone with 105,000 g microsomes of human fetal liver at midpregnancy. The identity of 16α-hydroxyprogesterone was proved by crystallizations to constant specific activity and by its behavior on thin-layer chromatography and gas-liquid chromatography as well as by gas chromatography-mass spectrometry.

Original languageEnglish (US)
Pages (from-to)249-260
Number of pages12
JournalSteroids
Volume12
Issue number2
DOIs
StatePublished - Aug 1968

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Endocrinology
  • Pharmacology
  • Clinical Biochemistry
  • Organic Chemistry

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