Biopsy of a choroidal melanoma using transvitreal pars plana vitrectomy

Determining when a previously benign choroidal nevi becomes malignant can be challenging, as traditional biopsy methods are often invasive and can lead to secondary complications such as endophthalmitis and vitreous hemorrhage. Using a transvitreal approach with the 27-gauge vitrectomy system provides several advantages, including direct visualization, theoretically lower risk of inadvertent seeding, and collection of a larger sample size. In this video, the authors present their technique for transvitreal biopsy of choroidal lesions using the 27-gauge vitreous cutter.