Biophysical attributes of an in vitro spinal cord surrogate for use in developing an intradural neuromodulation system

M. A. Howard, M. Utz, T. J. Brennan, B. D. Dalm, S. Viljoen, J. K. Kanwal, G. T. Gillies

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

We have developed a spinal cord surrogate for use in testing a pial-surface spinal cord stimulator. Our surrogate is of a commercially available silicone mix, has an oval cross-sectional area that matches that of actual human spinal cord at the lower thoracic level, and has measured values of durometer A (10.96 ± 1.68), durometer O (14.76 ± 1.48), and durometer OO (50.24 ± 2.65). These correspond to model-inferred elastic moduli of 0.41 to 0.44 MPa, which match well with the existing low-strain rate measurements of ex vivo human spinal cord. Upcoming applications for this surrogate in developmental studies of the new stimulator system are discussed.

Original languageEnglish (US)
Article number074701
JournalJournal of Applied Physics
Volume110
Issue number7
DOIs
StatePublished - Oct 1 2011

ASJC Scopus subject areas

  • Physics and Astronomy(all)

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