This chapter delineates current efforts for the development of novel, micro technology assisted modalities for the delivery of pharmaceuticals, which may help address the needs. Biodegradable polymer nanoparticles can provide sustained release from layers of diffuse drugs. Remote controlled-release may include sensing magnetic fields ultrasound and electric current which in itself naturally suggests the integration of microelectromechanical systems (MEMS) and bioMEMS technologies on the drug-delivery platform. The chapter also focuses on reviewing current micro technology-based drug-delivery devices and enabling technologies, and in particular micro fabricated needles, nanoporous membranes, implantable devices, and microcapsules for oral and parenteral drug delivery. Drug delivery technology is envisioned to support new neuro pharmacology research for treatment of neurological disorders. The implantable drug-delivery system incorporates multiple complex functionalities that can allow for self or remotely regulated dispensation of precisely controlled therapeutic agents. A large number of new biological drugs are being discovered, developed, and licensed that translates into expected further growth of the pharmaceutical market and the demand for alternative drug delivery device.
|Original language||English (US)|
|Title of host publication||Lab-on-a-Chip|
|Subtitle of host publication||Miniaturized Systems for (Bio) Chemical Analysis and Synthesis|
|Number of pages||17|
|State||Published - Jan 1 2003|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)