Abstract
Amyloid precursor protein (APP) is a single transmembrane protein that undergoes sequential proteolysis to generate multiple peptides, including the amyloid β -peptide (A β) - the major component of the senile plaques that are diagnostic hallmarks of Alzheimer’s disease (AD).
Original language | English (US) |
---|---|
Title of host publication | Amyloid Precursor Protein |
Subtitle of host publication | A Practical Approach |
Publisher | CRC Press |
Pages | 1-17 |
Number of pages | 17 |
ISBN (Electronic) | 9780203492185 |
ISBN (Print) | 9780849322457 |
State | Published - Jan 1 2004 |
ASJC Scopus subject areas
- General Biochemistry, Genetics and Molecular Biology
- General Neuroscience