TY - JOUR
T1 - Bioavailability of tritiated 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) administered to Holstein dairy cows
AU - Jones, D.
AU - Safe, S.
AU - Morcom, E.
AU - Holcomb, M.
AU - Coppock, C.
AU - Ivie, W.
N1 - Funding Information:
This work was supported by the U.S. Environmental Protection Agency cooperative agreement CR812614-01 and the Texas Agricultural Experiment Station, $6617, but does not necessarily reflect the views of these agencies. No official endorsement should be inferred.
PY - 1987
Y1 - 1987
N2 - Holstein dairy cows weighing from 500 to 650 kg were given tritiated TCDD on crushed grain at a dosage level of either 75 or 0.05 μg/kg body weight, per os. The higher dosed animal was killed on day 7 while the 2 lower dosed animals were killed on day 14. In both the high and low dosed animals, radioactivity was eliminated mainly in the feces, but also in milk and urine. The major portion of the administered dose was eliminated via these routes in the first several days post-treatment. Tissue residues were found to be the highest in fat, followed by liver, kidney, muscle and brain.
AB - Holstein dairy cows weighing from 500 to 650 kg were given tritiated TCDD on crushed grain at a dosage level of either 75 or 0.05 μg/kg body weight, per os. The higher dosed animal was killed on day 7 while the 2 lower dosed animals were killed on day 14. In both the high and low dosed animals, radioactivity was eliminated mainly in the feces, but also in milk and urine. The major portion of the administered dose was eliminated via these routes in the first several days post-treatment. Tissue residues were found to be the highest in fat, followed by liver, kidney, muscle and brain.
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U2 - 10.1016/0045-6535(87)90161-5
DO - 10.1016/0045-6535(87)90161-5
M3 - Article
AN - SCOPUS:18244414793
SN - 0045-6535
VL - 16
SP - 1743
EP - 1748
JO - Chemosphere
JF - Chemosphere
IS - 8-9
ER -