Bioanalysis of polychlorinated dibenzofuran and dibenzo-p-dioxin mixtures in fly ash

T. Sawyer; S. Bandiera; S. Safe; O. Hutzinger; K. Olie

doi:10.1016/0045-6535(83)90205-9

Bioanalysis of polychlorinated dibenzofuran and dibenzo-p-dioxin mixtures in fly ash

T. Sawyer, S. Bandiera, S. Safe, O. Hutzinger, K. Olie

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

The biologic activities of the polychlorinated dibenzofuran and dibenzo-p-dioxin fractions from fly ash extracts are assessed by measuring their potencies as inducers of ethoxyresorufin 0-deethylase and aryl hydrocarbon hydroxylase in rat hepatoma H-4-II E cells and their binding affinities to the cytosolic receptor protein. The utility of these bioassays for the analysis of the toxic halogenated aryl hydrocarbons is discussed.

Original language	English (US)
Pages (from-to)	529-536
Number of pages	8
Journal	Chemosphere
Volume	12
Issue number	4-5
DOIs	https://doi.org/10.1016/0045-6535(83)90205-9
State	Published - 1983

ASJC Scopus subject areas

Environmental Engineering
Environmental Chemistry
General Chemistry
Pollution
Health, Toxicology and Mutagenesis

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10.1016/0045-6535(83)90205-9

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abstract = "The biologic activities of the polychlorinated dibenzofuran and dibenzo-p-dioxin fractions from fly ash extracts are assessed by measuring their potencies as inducers of ethoxyresorufin 0-deethylase and aryl hydrocarbon hydroxylase in rat hepatoma H-4-II E cells and their binding affinities to the cytosolic receptor protein. The utility of these bioassays for the analysis of the toxic halogenated aryl hydrocarbons is discussed.",

author = "T. Sawyer and S. Bandiera and S. Safe and O. Hutzinger and K. Olie",

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T1 - Bioanalysis of polychlorinated dibenzofuran and dibenzo-p-dioxin mixtures in fly ash

AU - Sawyer, T.

AU - Bandiera, S.

AU - Safe, S.

AU - Hutzinger, O.

AU - Olie, K.

PY - 1983

Y1 - 1983

N2 - The biologic activities of the polychlorinated dibenzofuran and dibenzo-p-dioxin fractions from fly ash extracts are assessed by measuring their potencies as inducers of ethoxyresorufin 0-deethylase and aryl hydrocarbon hydroxylase in rat hepatoma H-4-II E cells and their binding affinities to the cytosolic receptor protein. The utility of these bioassays for the analysis of the toxic halogenated aryl hydrocarbons is discussed.

AB - The biologic activities of the polychlorinated dibenzofuran and dibenzo-p-dioxin fractions from fly ash extracts are assessed by measuring their potencies as inducers of ethoxyresorufin 0-deethylase and aryl hydrocarbon hydroxylase in rat hepatoma H-4-II E cells and their binding affinities to the cytosolic receptor protein. The utility of these bioassays for the analysis of the toxic halogenated aryl hydrocarbons is discussed.

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U2 - 10.1016/0045-6535(83)90205-9

DO - 10.1016/0045-6535(83)90205-9

M3 - Article

AN - SCOPUS:0020528493

SN - 0045-6535

VL - 12

SP - 529

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JO - Chemosphere

JF - Chemosphere

IS - 4-5

ER -

Bioanalysis of polychlorinated dibenzofuran and dibenzo-p-dioxin mixtures in fly ash

Abstract

ASJC Scopus subject areas

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