The biologic activities of the polychlorinated dibenzofuran and dibenzo-p-dioxin fractions from fly ash extracts are assessed by measuring their potencies as inducers of ethoxyresorufin 0-deethylase and aryl hydrocarbon hydroxylase in rat hepatoma H-4-II E cells and their binding affinities to the cytosolic receptor protein. The utility of these bioassays for the analysis of the toxic halogenated aryl hydrocarbons is discussed.
ASJC Scopus subject areas
- Environmental Engineering
- Environmental Chemistry
- Health, Toxicology and Mutagenesis