Bioanalysis of polychlorinated dibenzofuran and dibenzo-p-dioxin mixtures in fly ash

T. Sawyer, S. Bandiera, S. Safe, O. Hutzinger, K. Olie

Research output: Contribution to journalArticle

33 Scopus citations

Abstract

The biologic activities of the polychlorinated dibenzofuran and dibenzo-p-dioxin fractions from fly ash extracts are assessed by measuring their potencies as inducers of ethoxyresorufin 0-deethylase and aryl hydrocarbon hydroxylase in rat hepatoma H-4-II E cells and their binding affinities to the cytosolic receptor protein. The utility of these bioassays for the analysis of the toxic halogenated aryl hydrocarbons is discussed.

Original languageEnglish (US)
Pages (from-to)529-536
Number of pages8
JournalChemosphere
Volume12
Issue number4-5
DOIs
StatePublished - 1983
Externally publishedYes

ASJC Scopus subject areas

  • Environmental Engineering
  • Environmental Chemistry
  • Chemistry(all)
  • Pollution
  • Health, Toxicology and Mutagenesis

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