Bioactive polypyrrole thin films with conductimetric response to analyte

Anthony Guiseppi-Elie, J. M. Tour, D. L. Allara, N. F. Sheppard

Research output: Contribution to journalConference articlepeer-review

6 Scopus citations


Thin films of electroconductive poly[pyrrole-co-3-(1-pyrrolyl)propionic acid] were prepared by electropolymerization onto 3-aminopropyltrimethoxysilane modified and 3-(1-pyrrolyl)propionic acid derivatized interdigitated microsensor electrode (IME) arrays. The ω-(1-pyrrolyl) moiety on the surface of the device provides for specific adhesion of the polymer film to the device and the (N-pyrrolyl)propionic acid moiety on the polymer backbone provides for covalent attachment of bioactive molecules, such as biotin and urease, to the polymer surface. The immobilized, bioactive urease produces an ON/OFF conductimetric response traceable to analyte concentration.

Original languageEnglish (US)
Pages (from-to)439-444
Number of pages6
JournalMaterials Research Society Symposium - Proceedings
StatePublished - Jan 1 1996
EventProceedings of the 1995 MRS Fall Meeting - Boston, MA, USA
Duration: Nov 26 1995Dec 1 1995

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering


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