TY - JOUR
T1 - Bilateral Sixth Nerve Palsy and Nasal Voice in Two Sisters as a Variant of Guillan–Barré Syndrome
AU - Pellegrini, Francesco
AU - Wang, Margaret
AU - Romeo, Napoleone
AU - Lee, Andrew G.
N1 - Publisher Copyright:
© 2018, © 2018 The Authors.
PY - 2018/10
Y1 - 2018/10
N2 - A 6-year-old girl with acute pharyngitis presented with complaints of hypernasal speech and double vision. Examination revealed a bilateral abduction deficit associated with soft palate palsy causing rhinolalia aperta. Cerebrospinal fluid analysis showed albuminocytologic dissociation. Her sister also suffered from the same disorder, albeit milder, 1 month before. After treatment with intravenous immunoglobulin and steroids, the patient made a full recovery. After the case report, a brief discussion of Miller Fisher syndrome, Guillan–Barré syndrome, and their variants is made. This case highlights that bilateral sixth nerve palsy and rhinolalia aperta in the absence of ataxia should still raise suspicion for these autoimmune conditions that may rarely and atypically present in siblings.
AB - A 6-year-old girl with acute pharyngitis presented with complaints of hypernasal speech and double vision. Examination revealed a bilateral abduction deficit associated with soft palate palsy causing rhinolalia aperta. Cerebrospinal fluid analysis showed albuminocytologic dissociation. Her sister also suffered from the same disorder, albeit milder, 1 month before. After treatment with intravenous immunoglobulin and steroids, the patient made a full recovery. After the case report, a brief discussion of Miller Fisher syndrome, Guillan–Barré syndrome, and their variants is made. This case highlights that bilateral sixth nerve palsy and rhinolalia aperta in the absence of ataxia should still raise suspicion for these autoimmune conditions that may rarely and atypically present in siblings.
KW - Bilateral sixth nerve palsy
KW - Guillan–Barré syndrome
KW - Miller Fisher syndrome
KW - polyneuritis cranialis
KW - rhinolalia
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U2 - 10.1080/01658107.2017.1420085
DO - 10.1080/01658107.2017.1420085
M3 - Article
C2 - 30258478
AN - SCOPUS:85041010213
SN - 0165-8107
VL - 42
SP - 306
EP - 308
JO - Neuro-Ophthalmology
JF - Neuro-Ophthalmology
IS - 5
ER -