Basic Concepts of Hemorheology in Microvascular Hemodynamics

Shannan K. Hamlin; Penelope S. Benedik

doi:10.1016/j.ccell.2014.04.005

Basic Concepts of Hemorheology in Microvascular Hemodynamics

Shannan K. Hamlin, Penelope S. Benedik

Center for Nursing Research, Education and Practice

Research output: Contribution to journal › Review article › peer-review

22 Scopus citations

Abstract

Blood rheology, or hemorheology, involves the flow and deformation behavior of blood and its formed elements (ie, erythrocytes, leukocytes, platelets). The adequacy of blood flow to meet metabolic demands through large circulatory vessels depends highly on vascular control mechanisms. However, the extent to which rheologic properties of blood contribute to vascular flow resistance, particularly in the microcirculation, is becoming more appreciated. Current evidence suggests that microvascular blood flow is determined by local vessel resistance and hemorheologic factors such as blood viscosity, erythrocyte deformability, and erythrocyte aggregation. Such knowledge will aid clinicians caring for patients with hemodynamic alterations.

Original language	English (US)
Pages (from-to)	337-344
Number of pages	8
Journal	Critical Care Nursing Clinics of North America
Volume	26
Issue number	3
DOIs	https://doi.org/10.1016/j.ccell.2014.04.005
State	Published - Sep 2014

Keywords

Blood flow
Erythrocyte aggregation
Erythrocyte deformability
Hemodynamics
Hemorheology
Microvascular
Tissue perfusion
Viscosity

ASJC Scopus subject areas

Critical Care

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title = "Basic Concepts of Hemorheology in Microvascular Hemodynamics",

abstract = "Blood rheology, or hemorheology, involves the flow and deformation behavior of blood and its formed elements (ie, erythrocytes, leukocytes, platelets). The adequacy of blood flow to meet metabolic demands through large circulatory vessels depends highly on vascular control mechanisms. However, the extent to which rheologic properties of blood contribute to vascular flow resistance, particularly in the microcirculation, is becoming more appreciated. Current evidence suggests that microvascular blood flow is determined by local vessel resistance and hemorheologic factors such as blood viscosity, erythrocyte deformability, and erythrocyte aggregation. Such knowledge will aid clinicians caring for patients with hemodynamic alterations.",

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AU - Benedik, Penelope S.

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AB - Blood rheology, or hemorheology, involves the flow and deformation behavior of blood and its formed elements (ie, erythrocytes, leukocytes, platelets). The adequacy of blood flow to meet metabolic demands through large circulatory vessels depends highly on vascular control mechanisms. However, the extent to which rheologic properties of blood contribute to vascular flow resistance, particularly in the microcirculation, is becoming more appreciated. Current evidence suggests that microvascular blood flow is determined by local vessel resistance and hemorheologic factors such as blood viscosity, erythrocyte deformability, and erythrocyte aggregation. Such knowledge will aid clinicians caring for patients with hemodynamic alterations.

KW - Blood flow

KW - Erythrocyte aggregation

KW - Erythrocyte deformability

KW - Hemodynamics

KW - Hemorheology

KW - Microvascular

KW - Tissue perfusion

KW - Viscosity

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ER -

Basic Concepts of Hemorheology in Microvascular Hemodynamics

Abstract

Keywords

ASJC Scopus subject areas

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