Basic Concepts of Hemorheology in Microvascular Hemodynamics

Shannan K. Hamlin, Penelope S. Benedik

Research output: Contribution to journalReview article

11 Scopus citations

Abstract

Blood rheology, or hemorheology, involves the flow and deformation behavior of blood and its formed elements (ie, erythrocytes, leukocytes, platelets). The adequacy of blood flow to meet metabolic demands through large circulatory vessels depends highly on vascular control mechanisms. However, the extent to which rheologic properties of blood contribute to vascular flow resistance, particularly in the microcirculation, is becoming more appreciated. Current evidence suggests that microvascular blood flow is determined by local vessel resistance and hemorheologic factors such as blood viscosity, erythrocyte deformability, and erythrocyte aggregation. Such knowledge will aid clinicians caring for patients with hemodynamic alterations.

Original languageEnglish (US)
Pages (from-to)337-344
Number of pages8
JournalCritical Care Nursing Clinics of North America
Volume26
Issue number3
DOIs
StatePublished - Sep 2014

Keywords

  • Blood flow
  • Erythrocyte aggregation
  • Erythrocyte deformability
  • Hemodynamics
  • Hemorheology
  • Microvascular
  • Tissue perfusion
  • Viscosity

ASJC Scopus subject areas

  • Critical Care

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