Basic aspects of estrogen action

Stefan Nilsson, Jan Åke Gustafsson

Research output: Contribution to journalReview articlepeer-review

115 Scopus citations

Abstract

Estrogen signaling has turned out to be much more complex and exciting than previously thought; the paradigm shift in our understanding of estrogen action came in 1996, when the presence of a new estrogen receptor (ER), ERβ, was reported. An intricate interplay between the classical ERα and the novel ERβ is of paramount importance for the final biological effect of estrogen in different target cells.

Original languageEnglish (US)
Pages (from-to)360-366
Number of pages7
JournalBreast Cancer Research
Volume2
Issue number5
DOIs
StatePublished - 2000

Keywords

  • Breast
  • Central nervous system
  • Estrogen receptor β
  • Estrogen receptor knockout mice
  • Heterodimerization
  • Prostate
  • Uterus

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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