Basic aspects of estrogen action

Stefan Nilsson; Jan Åke Gustafsson

doi:10.1186/bcr81

Basic aspects of estrogen action

Stefan Nilsson, Jan Åke Gustafsson

Research Institute

Research output: Contribution to journal › Review article › peer-review

118 Scopus citations

Abstract

Estrogen signaling has turned out to be much more complex and exciting than previously thought; the paradigm shift in our understanding of estrogen action came in 1996, when the presence of a new estrogen receptor (ER), ERβ, was reported. An intricate interplay between the classical ERα and the novel ERβ is of paramount importance for the final biological effect of estrogen in different target cells.

Original language	English (US)
Pages (from-to)	360-366
Number of pages	7
Journal	Breast Cancer Research
Volume	2
Issue number	5
DOIs	https://doi.org/10.1186/bcr81
State	Published - 2000

Keywords

Breast
Central nervous system
Estrogen receptor β
Estrogen receptor knockout mice
Heterodimerization
Prostate
Uterus

ASJC Scopus subject areas

Cancer Research
Oncology

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10.1186/bcr81

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title = "Basic aspects of estrogen action",

abstract = "Estrogen signaling has turned out to be much more complex and exciting than previously thought; the paradigm shift in our understanding of estrogen action came in 1996, when the presence of a new estrogen receptor (ER), ERβ, was reported. An intricate interplay between the classical ERα and the novel ERβ is of paramount importance for the final biological effect of estrogen in different target cells.",

keywords = "Breast, Central nervous system, Estrogen receptor β, Estrogen receptor knockout mice, Heterodimerization, Prostate, Uterus",

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AU - Gustafsson, Jan Åke

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AB - Estrogen signaling has turned out to be much more complex and exciting than previously thought; the paradigm shift in our understanding of estrogen action came in 1996, when the presence of a new estrogen receptor (ER), ERβ, was reported. An intricate interplay between the classical ERα and the novel ERβ is of paramount importance for the final biological effect of estrogen in different target cells.

KW - Breast

KW - Central nervous system

KW - Estrogen receptor β

KW - Estrogen receptor knockout mice

KW - Heterodimerization

KW - Prostate

KW - Uterus

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Basic aspects of estrogen action

Abstract

Keywords

ASJC Scopus subject areas

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