Basic aspects of estrogen action

Stefan Nilsson, Jan Åke Gustafsson

    Research output: Contribution to journalReview articlepeer-review

    125 Scopus citations

    Abstract

    Estrogen signaling has turned out to be much more complex and exciting than previously thought; the paradigm shift in our understanding of estrogen action came in 1996, when the presence of a new estrogen receptor (ER), ERβ, was reported. An intricate interplay between the classical ERα and the novel ERβ is of paramount importance for the final biological effect of estrogen in different target cells.

    Original languageEnglish (US)
    Pages (from-to)360-366
    Number of pages7
    JournalBreast Cancer Research
    Volume2
    Issue number5
    DOIs
    StatePublished - 2000

    Keywords

    • Breast
    • Central nervous system
    • Estrogen receptor β
    • Estrogen receptor knockout mice
    • Heterodimerization
    • Prostate
    • Uterus

    ASJC Scopus subject areas

    • Cancer Research
    • Oncology

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