Bacterial adherence to pharyngeal cells during viral infection

Victor Fainstein, D. M. Musher, T. R. Cate

Research output: Contribution to journalArticlepeer-review

122 Scopus citations

Abstract

Adherence of bacteria to pharyngeal cells from patients with naturally acquired acute respiratory illness and from volunteers experimentally infected with influenza virus vaccine was studied. Increased adherence of Staphylococcus aureus was found in both groups. In addition, Haemophilus influenzae and Streptococcus pneumoniae type I adhered in increased numbers to cells from volunteers experimentally infected with influenza virus. Alterations in mucosal cells leading to increased bacterial adherence may play a role in the pathogenesis of suprainfection by these organisms in patients with viral respiratory diseases.

Original languageEnglish (US)
Pages (from-to)172-176
Number of pages5
JournalJournal of Infectious Diseases
Volume141
Issue number2
DOIs
StatePublished - 1980

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases

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