Avian metabolism of halogenated biphenyls

D. H. Jones, J. Kohli, S. Safe

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

1. The metabolism of several halogenated biphenyls has been studied using poultry as a model system. The substrates 4-chlorobiphenyl and 4-bromobiphenyl each yielded two metabolites (4'chloro-4-biphenylol, 4'chloro-3,4-biphenyldiol; 4'bromo-4-biphenylol, 4'bromo-3,4-biphenyldiol), while 4,4'dichlorobiphenyl yielded only one metabolite (4,4'dichloro-3-biphenylol). 2. Metabolites were not found in eggs collected for 7 days following the administration of the substrate.

Original languageEnglish (US)
Pages (from-to)733-736
Number of pages4
JournalXenobiotica
Volume9
Issue number12
DOIs
StatePublished - 1979

ASJC Scopus subject areas

  • Biochemistry
  • Toxicology
  • Pharmacology
  • Health, Toxicology and Mutagenesis

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