Autophagy: Cellular defense to excessive inflammation

Eun Kyeong Jo, Dong Min Shin, Augustine M.K. Choi

Research output: Contribution to journalShort survey

25 Scopus citations

Abstract

Autophagy can orchestrate a variety of cellular responses to dangerous stimuli. Our understanding of the physiologic roles of autophagy has recently expanded; in addition to its other roles, autophagy now appears to play an essential role in regulating inflammatory responses. This review describes recent findings concerning the roles and mechanisms of autophagy in controlling excessive inflammation.

Original languageEnglish (US)
Pages (from-to)119-125
Number of pages7
JournalMicrobes and Infection
Volume14
Issue number2
DOIs
StatePublished - Feb 2012

Keywords

  • Autophagy
  • Autophagy-related genes
  • Cargo receptors
  • Inflammasome
  • Inflammation
  • Pattern recognition receptors

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Infectious Diseases

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