Autophagy and alzheimer’s disease

Sheng Chen, Qinming Zhou, You Ni, Weidong Le

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Alzheimer’s disease (AD) is the most common type of dementia and is characterized by progressive cognitive decline. Increasing evidence has demonstrated that the autophagic process plays an important role in AD. In this chapter, we will discuss the role of autophagy in the pathogenesis of AD and other types of dementia, including dementia with Lewy bodies (DLB), frontotemporal dementia (FTD), vascular dementia (VD) and prion diseases. In addition, we will discuss autophagy-targeted therapies as future treatments for AD.

Original languageEnglish (US)
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer
Pages3-19
Number of pages17
DOIs
StatePublished - 2020

Publication series

NameAdvances in Experimental Medicine and Biology
Volume1207
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019

Keywords

  • Alzheimer’s disease
  • Autophagy
  • Dementia

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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