Autonomic function after botulinum toxin type A or B: A double-blind, randomized trial

Ron Tintner, R. Gross, U. F. Winzer, K. A. Smalky, J. Jankovic

Research output: Contribution to journalArticle

62 Scopus citations

Abstract

To compare autonomic effects of botulinum toxin (BTX), we randomized patients with cervical dystonia to receive either BTX-A or BTX-B in a double-blind manner. Efficacy and physiologic questionnaire measures of autonomic function were assessed at baseline and 2 weeks after injection. Patients treated with BTX-B had less saliva production (p < 0.01) and greater severity of constipation (p = 0.037) than those treated with BTX-A, but did not differ in other tests of autonomic functions.

Original languageEnglish (US)
Pages (from-to)765-767
Number of pages3
JournalNeurology
Volume65
Issue number5
DOIs
StatePublished - Sep 13 2005

ASJC Scopus subject areas

  • Clinical Neurology

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