Autonomic Dysfunction and Sleep Apnea in Olivopontocerebellar Degeneration

Sudhansu Chokroverty, Rajesh Sachdeo, Joseph C. Masdeu

Research output: Contribution to journalArticle

58 Scopus citations

Abstract

We studied ten men with olivopontocerebellar degeneration. Our findings of the autonomic deficits as manifested by orthostatic hypotension, impaired Valsalva's response, abnormal findings on cold pressor and mental arithmetic tests, and plasma renin and norepinephrine abnormalities in some patients with olivopontocerebellar degeneration suggested a defective central control of the sympathetic nervous system. Five patients had sleep apnea. Autonomic dysfunction and sleep apnea in olivopontocerebellar degeneration may result from degenerative lesions in the cerebellum and the brain stem.

Original languageEnglish (US)
Pages (from-to)926-931
Number of pages6
JournalArchives of neurology
Volume41
Issue number9
DOIs
StatePublished - Jan 1 1984

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology

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