Automating and simplifying the SOFA score in critically ill patients with cancer

Joseph L. Nates, Marylou Cárdenas-Turanzas, Chris Wakefield, Susannah Kish Wallace, Andrew Shaw, Joshua A. Samuels, Joe Ensor, Kristen J. Price

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


The aim was to demonstrate the performance of a modified version of the Sequential Organ Failure Assessment (SOFA) score to predict mortality in medical and surgical patients with cancer. We performed an electronic retrospective review of databases. We included adult patients with cancer admitted into a 53-bed ICU over 28 months. We electronically calculated a modified SOFA (mSOFA) score at admission. A majority of the patients were admitted into the surgical ICU. Of 328 nonsurvivors, 85.1 per cent were medical patients and only 14.9 per cent surgical patients. The mean admission mSOFA scores for medical and surgical patients were 4.7 ± 3.2 and 1.7 ± 1.9, respectively. The overall area under the curve (AUC) of the mSOFA score was 0.84. The AUCs for medical and surgical patients were 0.72 and 0.78, respectively. Our results demonstrate that electronic assessment of mSOFA score has potential in resource allocation decisions as well as in critical care outreach programs.

Original languageEnglish (US)
Pages (from-to)35-47
Number of pages13
JournalHealth Informatics Journal
Issue number1
StatePublished - Mar 2010


  • Cancer
  • Critically ill
  • Health status index
  • Mortality
  • Outcomes
  • ROC curve analysis

ASJC Scopus subject areas

  • Health Informatics


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