Automated quantitation of zebrafish somites in high-throughput screens

Jianfeng Lu; Tianming Liu; Jingxín Nie; Jie Ding; Jinmin Zhu; Jingyu Yang; Lei Guo; Weiming Xia; Stephen T.C. Wong

doi:10.1109/LSSA.2006.250389

Automated quantitation of zebrafish somites in high-throughput screens

Jianfeng Lu, Tianming Liu, Jingxín Nie, Jie Ding, Jinmin Zhu, Jingyu Yang, Lei Guo, Weiming Xia, Stephen T.C. Wong

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

4 Scopus citations

Abstract

With the availability of high-throughput imaging machines and large number of zebrafish embryos, zebrafish is by far one of the most cost-effective vertebrate systems for high-throughput or high-content screens. With the tremendous amount of images generated from large numbers of zebrafish, computerized image analysis for accurate and efficient data interpretation becomes essential. This paper presents an automated algorithm for quantitation of zebrafish somite in high-throughput screen. Preliminary evaluation results are shown to demonstrate the performance of the algorithm, This algorithm has been integrated into our CBI Platform.

Original language	English (US)
Title of host publication	2006 IEEE/NLM Life Science Systems and Applications Workshop, LiSA 2006
DOIs	https://doi.org/10.1109/LSSA.2006.250389
State	Published - 2006
Event	2006 IEEE/NLM Life Science Systems and Applications Workshop, LiSA 2006 - Bethesda, MD, United States Duration: Jul 13 2006 → Jul 14 2006

Publication series

Name	2006 IEEE/NLM Life Science Systems and Applications Workshop, LiSA 2006

Other

Other	2006 IEEE/NLM Life Science Systems and Applications Workshop, LiSA 2006
Country/Territory	United States
City	Bethesda, MD
Period	7/13/06 → 7/14/06

ASJC Scopus subject areas

Health(social science)
Assessment and Diagnosis
Medicine(all)
Health Information Management
Electrical and Electronic Engineering
Human-Computer Interaction
Computer Science Applications
Signal Processing

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10.1109/LSSA.2006.250389

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Lu, J., Liu, T., Nie, J., Ding, J., Zhu, J., Yang, J., Guo, L., Xia, W., & Wong, S. T. C. (2006). Automated quantitation of zebrafish somites in high-throughput screens. In 2006 IEEE/NLM Life Science Systems and Applications Workshop, LiSA 2006 [4015790] (2006 IEEE/NLM Life Science Systems and Applications Workshop, LiSA 2006). https://doi.org/10.1109/LSSA.2006.250389

Automated quantitation of zebrafish somites in high-throughput screens. / Lu, Jianfeng; Liu, Tianming; Nie, Jingxín; Ding, Jie; Zhu, Jinmin; Yang, Jingyu; Guo, Lei; Xia, Weiming ; Wong, Stephen T.C.

2006 IEEE/NLM Life Science Systems and Applications Workshop, LiSA 2006. 2006. 4015790 (2006 IEEE/NLM Life Science Systems and Applications Workshop, LiSA 2006).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Lu, J, Liu, T, Nie, J, Ding, J, Zhu, J, Yang, J, Guo, L, Xia, W & Wong, STC 2006, Automated quantitation of zebrafish somites in high-throughput screens. in 2006 IEEE/NLM Life Science Systems and Applications Workshop, LiSA 2006., 4015790, 2006 IEEE/NLM Life Science Systems and Applications Workshop, LiSA 2006, 2006 IEEE/NLM Life Science Systems and Applications Workshop, LiSA 2006, Bethesda, MD, United States, 7/13/06. https://doi.org/10.1109/LSSA.2006.250389

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AU - Guo, Lei

AU - Xia, Weiming

AU - Wong, Stephen T.C.

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AB - With the availability of high-throughput imaging machines and large number of zebrafish embryos, zebrafish is by far one of the most cost-effective vertebrate systems for high-throughput or high-content screens. With the tremendous amount of images generated from large numbers of zebrafish, computerized image analysis for accurate and efficient data interpretation becomes essential. This paper presents an automated algorithm for quantitation of zebrafish somite in high-throughput screen. Preliminary evaluation results are shown to demonstrate the performance of the algorithm, This algorithm has been integrated into our CBI Platform.

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SN - 9781424402786

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ER -

Automated quantitation of zebrafish somites in high-throughput screens

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ASJC Scopus subject areas

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