@article{4085d585317747f5817e7fa6210f2a3a,
title = "Atherogenesis and the arginine hypothesis.",
abstract = "In patients who have elevated levels of plasma ADMA, a relative deficiency of L-arginine has been found to contribute to the pathophysiology of athersclerosis, causing vasoconstriction, and accelerating atherogenesis. This finding--that there is a relative deficiency of L-arginine in atherosclerotic disease--is a breakthrough that will open new avenues of therapy.",
author = "Cooke, {J. P.} and Oka, {R. K.}",
note = "Funding Information: This manuscript was supported in part by grants from the National Heart, Lung and Blood Institute (R01 HL58638; to Dr. Cooke) and from the National Institute of Nursing Research (NR00150-02; to Dr Oka). Dr. Cooke is an Established Investigator of the American Heart Association. He is the founder of Cooke Pharma, maker of an arginine-enriched medical food. Copyright: This record is sourced from MEDLINE{\textregistered}/PubMed{\textregistered}, a database of the U.S. National Library of Medicine",
year = "2001",
month = may,
doi = "10.1007/s11883-001-0068-x",
language = "English (US)",
volume = "3",
pages = "252--259",
journal = "Current Atherosclerosis Reports",
issn = "1523-3804",
publisher = "Current Medicine Group",
number = "3",
}