In patients who have elevated levels of plasma ADMA, a relative deficiency of L-arginine has been found to contribute to the pathophysiology of athersclerosis, causing vasoconstriction, and accelerating atherogenesis. This finding--that there is a relative deficiency of L-arginine in atherosclerotic disease--is a breakthrough that will open new avenues of therapy.

Original languageEnglish (US)
Pages (from-to)252-259
Number of pages8
JournalCurrent Atherosclerosis Reports
Issue number3
StatePublished - May 2001

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


Dive into the research topics of 'Atherogenesis and the arginine hypothesis.'. Together they form a unique fingerprint.

Cite this