Association between genital tract cytomegalovirus infection and bacterial vaginosis

Shannon A. Ross, Zdenek Novak, Guha Ashrith, Lisa B. Rivera, William J. Britt, Spencer Hedges, Jane R. Schwebke, Suresh Boppana

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

Women with sexually transmitted diseases (STDs) and bacterial vaginosis (BV) have increased rates of cytomegalovirus (CMV) seroprevalence and CMV seroconversion. To characterize the association between genital tract CMV infection and BV, vaginal wash specimens from 52 women attending an STD clinic were analyzed. Significantly more women with BV shed CMV in the lower genital tract than did women without BV. In addition, most of the women who were shedding CMV were infected with >1 virus strain. These results suggest that local CMV replication and infection with multiple CMV strains is facilitated by the presence of BV.

Original languageEnglish (US)
Pages (from-to)1727-1730
Number of pages4
JournalJournal of Infectious Diseases
Volume192
Issue number10
DOIs
StatePublished - Nov 15 2005

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases

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