Assignment of a novel protein tyrosine phosphatase gene (Hcph) to mouse chromosome 6

Taolin Yi, Debra J. Gilbert, Nancy A. Jenkins, Neal G. Copeland, James N. Ihle

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

Hematopoietic cell phosphatase (Hcph) was identified by amplification of conserved protein tyrosine phosphatase sequences from a myeloid cell line and is predominantly expressed in hematopoietic cells. Hcph is unique in containing two, tandemly repeated, src-homology 2 domains in the amino terminal region of the phosphatase. Using a genomic probe in interspecific backcross analysis, the murine Hcph gene maps to mouse Chromosome 6 and is tightly linked to the Tnfr-2 and Ly-4 genes.

Original languageEnglish (US)
Pages (from-to)793-795
Number of pages3
JournalGenomics
Volume14
Issue number3
DOIs
StatePublished - Nov 1992

ASJC Scopus subject areas

  • Genetics

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