TY - JOUR
T1 - Assessment of myocardial viability by cardiac MRI
AU - Al-Sabeq, Basil
AU - Nabi, Faisal
AU - Shah, Dipan J.
N1 - Funding Information:
D.J.S. receives salary support from the National Science Foundation (grant CNS-1646566) and the National Institutes of Health (1R01HL137763-01).
Publisher Copyright:
© 2019 Wolters Kluwer Health, Inc. All rights reserved.
PY - 2019/9/1
Y1 - 2019/9/1
N2 - Purpose of reviewLeft ventricular systolic dysfunction because of coronary artery disease is common, and ascertaining which patients will benefit from revascularization can be challenging. Viability testing is an accepted means by which to base this decision, with multiple noninvasive imaging modalities available for this purpose. This review aims to highlight the key role of cardiac magnetic resonance in myocardial viability assessment, with a focus on its unique strengths over other imaging modalities.Recent findingsTransmural extent of hyperenhancement with late gadolinium imaging has been shown to be greater acutely in ST elevation myocardial infarction patients undergoing primary percutaneous coronary intervention and regress at follow-up studies. An explanation for this reported phenomenon and an argument against redefining CMR viability criteria in the acute setting will be offered.SummaryAlthough not universally available, cardiac magnetic resonance is an exceptionally powerful and well tolerated imaging modality that should be considered when viability testing will influence patient management. Although observational outcomes data suggest a promising prognostic role for viability, randomized studies in this area are needed.
AB - Purpose of reviewLeft ventricular systolic dysfunction because of coronary artery disease is common, and ascertaining which patients will benefit from revascularization can be challenging. Viability testing is an accepted means by which to base this decision, with multiple noninvasive imaging modalities available for this purpose. This review aims to highlight the key role of cardiac magnetic resonance in myocardial viability assessment, with a focus on its unique strengths over other imaging modalities.Recent findingsTransmural extent of hyperenhancement with late gadolinium imaging has been shown to be greater acutely in ST elevation myocardial infarction patients undergoing primary percutaneous coronary intervention and regress at follow-up studies. An explanation for this reported phenomenon and an argument against redefining CMR viability criteria in the acute setting will be offered.SummaryAlthough not universally available, cardiac magnetic resonance is an exceptionally powerful and well tolerated imaging modality that should be considered when viability testing will influence patient management. Although observational outcomes data suggest a promising prognostic role for viability, randomized studies in this area are needed.
KW - cardiac magnetic resonance
KW - ischemic cardiomyopathy
KW - late gadolinium enhancement
KW - myocardial viability
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U2 - 10.1097/HCO.0000000000000656
DO - 10.1097/HCO.0000000000000656
M3 - Review article
C2 - 31394561
AN - SCOPUS:85070606700
SN - 0268-4705
VL - 34
SP - 502
EP - 509
JO - Current Opinion in Cardiology
JF - Current Opinion in Cardiology
IS - 5
ER -