Assessing the elasticity change of cataract lens with OCE

Chen Wu, Chih Hao Liu, Raksha Raghunathan, Manmohan Singh, Jiasong Li, Zhaolong Han, Kirill V. Larin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

Cataract is one of the most common degenerative diseases that causes blindness. Careful quantification of lens biomechanical properties can greatly assist in early detection of the disease as well as personalization of treatment procedures. In this study, we utilize a phase-sensitive optical coherence elastography (OCE) system to assess the effects of the cold cataract on the biomechanical properties of porcine crystalline lens in vitro. Relaxation rates of air puff induced elastic waves were measured on the same crystalline lens with and without cold cataract. Results demonstrate that the relaxation rate and, thus, associated elasticity of the porcine lens, increased due to the presence of cold cataract.

Original languageEnglish (US)
Title of host publicationOphthalmic Technologies XXVI
EditorsArthur Ho, Fabrice Manns, Per G. Soderberg
PublisherSPIE
ISBN (Electronic)9781628419276
DOIs
StatePublished - 2016
Event26th Conference on Ophthalmic Technologies - San Francisco, United States
Duration: Feb 13 2016Feb 14 2016

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume9693
ISSN (Print)1605-7422

Conference

Conference26th Conference on Ophthalmic Technologies
Country/TerritoryUnited States
CitySan Francisco
Period2/13/162/14/16

Keywords

  • cold cataract
  • elasticity
  • optical coherence elastography (OCE)

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Fingerprint

Dive into the research topics of 'Assessing the elasticity change of cataract lens with OCE'. Together they form a unique fingerprint.

Cite this