ARTreat project: Three-dimensional numerical simulation of plaque formation and development in the arteries

Nenad D. Filipovic, Nicolas Meunier, Zarko Milosevic, Nebojsa D. Zdravkovic, Milos R. Kojic, Dimitris Fotiadis, Oberdan Parodi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Scopus citations

Abstract

Atherosclerosis is a progressive disease characterized by the accumulation of lipids and fibrous elements in arteries. It is characterized by dysfunction of endothelium, vasculitis and accumulation of lipid, cholesterol and cell elements inside blood vessel wall. [n this study a continuum based approach for plaque formation and development in three-dimension is presented. The blood flow is simulated by the three-dimensional Navier-Stokes equations, together with the continuity equation while LDL transport in lumen of the vessel is coupled with Kedem-Katchalsky equations. The inflammatory process was solved using three additional reaction-diffusion partial differential equations. Three-dimensional model of the straight artery with initial mild constriction of 30% plaque for formation and development is presented.

Original languageEnglish (US)
Title of host publicationITAB 2010 - 10th International Conference on Information Technology and Applications in Biomedicine
Subtitle of host publicationEmerging Technologies for Patient Specific Healthcare
DOIs
StatePublished - 2010
Event10th International Conference on Information Technology and Applications in Biomedicine: Emerging Technologies for Patient Specific Healthcare, ITAB 2010 - Corfu, Greece
Duration: Nov 2 2010Nov 5 2010

Publication series

NameProceedings of the IEEE/EMBS Region 8 International Conference on Information Technology Applications in Biomedicine, ITAB

Other

Other10th International Conference on Information Technology and Applications in Biomedicine: Emerging Technologies for Patient Specific Healthcare, ITAB 2010
CountryGreece
CityCorfu
Period11/2/1011/5/10

ASJC Scopus subject areas

  • Computer Science Applications
  • Biomedical Engineering

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